The OBiO team has more than 10 years of CRO service experience in virus production.
· Adeno-associated virus (AAV)
· Lenti virus (LV)
· Adeno virus (ADV)
· Retro virus (RV)
· Herpes simplex virus (HSV)
· Other oncolytic virus
We have built comprehensive technology capability and been well equipped to serve our customer from lab scale process development to clinical phase III.
A well-established lab and experienced scientists are working on process development and quality study, fully focus on virus.
· Provide small scale virus for drug candidates’ study.
· Ecoli Fermentation process development to improve plasmid titer.
· Plasmid purification process development for best quality and high yield.
· HEK293T cell culture process development, either Microcarrier or suspension cell culture.
· Virus purification process development by Chromatography and UF/DF technical platform.
· Virus formulation study.
· Up and downstream process validation during clinical Phase II or Phase III.
· Resin/membrane life time study in downstream application.
· Assay method development for virus quality control.
· In-process sample test.
· Virus drug substance or product release test.
· Assay method qualification or validation.